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Cosmosil


Sample Separation Mode Packing Material USP Code Stationary
Phase
Special Features and Applications
Organic
Compounds
(low M.W.)
Reversed
Phase
3C18-EB L1 Octadecyl
Group
- Excellent for basic compounds
- 3 µm silica packing material
C18-MS-II L1 Octadecyl
Group
- Multi-purpose C18column
- Monofunctional silylation on ultra-pure silica gel for separation of the widest range of compounds
C18-AR-II L1 -Features strong acid resistance and suitable for acidic compounds and peptides
C18-PAQ L1 - Reversed phase column, compatible with 100% water based mobile phase.
- Suitable for hydrophilic compounds
Cholester L101 Cholesteryl
Group
- Usable under the same condition as C18
- Unique rigid cholesteryl structure improves separation
PBr  Pentabromobenzyl group  - Separate hydrohilic compounds in reversed-phase conditions
πNAP - Naphtylethyl 
Group
- Stronger π-π interaction than Phenyl column
PYE - Pyrenylethyl
Group
- Most powerful π-π interaction
NPE - Nitrophenylethyl 
Group
- Separation utilizing π-π interaction and dipole-dipole interaction
PBB-R - Pentabromobenzyl
Group
- Separation utilizing dispersion force
PFP  L43 Pentafluorophenyl
Group 
-Separation by dipole-dipole interactions.
CN-MS L10 Cyanopropyl 
Group
- Great reproducibility using isocratic elution mode
C22-AR-II - Docosyl
Group
- Alkyl chain columns except C18column
C8-MS L7 Octyl
Group
C4-MS L26 Butyl 
Group
TMS-MS L13 Trimethyl 
Group
PE-MS L11 Phenylethyl 
Group
- π-π interaction
Normal 
Phase
SL-II L3 - - Suitable for preparative separation
Hydrophilic
Interaction
HILIC L104 Triazole - Retains highly polar compounds that would not be retained in C18column
Monosaccharides
Oligosaccharides
Hydrophilic
Interaction
Sugar-D - Secondary/Tertiary Amine - Suitable for monosaccharides, oligosaccharides
NH2-MS L8 Aminopropyl 
Group
- Primary amine bonded column
Proteins Reversed
Phase
Protein-R L1 Octadecyl 
Group
- Provides improved separation, high recovery rate, and acid resistance
C18-AR-300 L1 Octadecyl
Group
- Wide pore type reversed phase columns
C8-AR-300 L7 Octyl
Group
C4-AR-300 L26 Butyl
Group
Ph-AR-300 L11 Phenyl
Group
Proteins Gel
Permeation 
Diol-120-II L20 Diol Group - Silica-based gel filtration column
- Sample MW (Protein) 5,000-100,000 Da
Diol-300-II - Silica-based gel filtration column
- Sample MW (Protein) 10,000-700,000 Da
Diol-1000-II  - Silica-based gel filtration column
- Sample MW (Water Soluble Polymer) 50,000 - 500,000 Da 
Ion-exchange Type Q   Quaternary Ammonium Type - Anion-exchange Type
- For Purification
- Target Sample: Acidic Proteins / DNA
Type Q-N   - Anion-exchange Type
- For Ultra-fast Analysis, Precise Analysis
- Target Sample: Acidic Proteins / DNA
Type S   Sulfopropyl Type - Cation-exchange Type
- For Purification
- Target Sample: Basic Proteins
Type S-N   - Cation-exchange Type
- For Ultra-fast Analysis, Precise Analysis
- Target Sample: Basic Proteins
Type M   Quaternary Ammonium Type/
Sulfopropyl Type
- Amphoteric ion-exchange Type
- For Purification
- Target Sample: All Proteins
Type M-N   - Amphoteric ion-exchange Type
- For Precise Analysis
- Target Sample: All Proteins
Hydrophobic
Interaction
HIC - - - Suitable for separation of peptide, and there is only a little less in enzyme activity and the teriary structure of proteins
Fullerenes - Buckyprep - Pyrenylpropyl 
Group
- Standard column for fullerene separation
Buckyprep-D - Nitro-carbazoyl Group - Designed for separation of fullerene derivatives
Buckyprep-M - Phenothiazinyl
Group
- Designed to separate metallofullerenes
PBB - Pentabromobenzyl
Group
- Designed for preparative separation of C60, C70
PYE - Pyrenylethyl 
Group
- Separation of Fullerenes and structural isomers
NPE - Nitrophenylethyl
Group
- Separation of derivatived fullerene
Carbon
Nanotubes
Gel 
Permeation
CNT   Hydrophilic 
Group
- separation of carbon nanotubes
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