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Davisil Media


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Davisil Chromatographic Silica

A wide range of Davisil® silica grades are available from 1kg to multi-ton quantities to meet your application, performance, and economic requirements.
Compared to 60Å silicas traditionally used for small molecule purification, the newly developed 35Å Davisil® silica has higher surface area. This can lead to up to 50% greater loading capacity and 50% reduction in solvent consumption making purification more productive with less impact on the environment.
The 4500Å Davisil® silica grade is especially designed for large molecules commonly purified in bioprocessing.

• Available in both normal phase bare silica and various bonding chemistries (C18, Amino, Diol, Cyano) for alternative selectivity.
• Wide selection of distinct pore diameters
  (30Å – 4500Å) for separation of a wide range of MW sizes.
• Available from 1kg to multi-ton quantities.
• Grace not only offers media for process purification but also column hardware, packing equipment, and process HPLC systems for optimized chromatographic performance.


Specifications
 

Normal Pore Size
Characteristic 35Å 60Å 150Å 250Å 500Å 1000Å  1500Å 2500Å 4500Å
Surface Area (m2/g) 700 550 330 285 80 40 25 17 10
Pore Volume (mL/g) 0.6 0.9 1.2 1.8 1.1 1.1 1.1 1.1 1.1
 pH (5% suspension) 5.7 7.3 7.3 7.5 8.0 9.0 9.0 9.0 9.5
H2O (weight %)† < 6% <6% <6% <6% <6% <6% <6% <6% <6%
Bulk Density (kg/m3) 720 530 350 210 370 370 370 370 370

  †Moisture content (% H20) can be tailored (increased or decreased) to meet customer requirements.

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